It is also linked with cardiovascular disease and cerebrovascular disease. More so, an increased mean platelet volume level can put a patient at risk for thrombosis. This includes hypertension and excessive smoking.
A low MPV can be caused by a certain types of drugs.A high MPV and high platelet count indicates that the bone marrow is producing too much platelets.It could also indicate hyperthyroidism (over production of thyroid hormones). If the platelet count is normal but the mean platelet volume is high, it could indicate chronic myeloid leukemia (over production of a specific type of white blood cells).This is common in patients with immune thrombocytopenia and pre-eclampsia. If the platelet count is low but the mean platelet volume is high, it indicates that there is a destruction in platelet.Purplish spots and rashes are also the reasons for PDW monitoring. It is also checked in patients with several episodes of nose bleeding. The doctor will thoroughly check PDW if the patient is suffering from unexplained bruising and excessive bleeding from small wounds and cuts. Platelet Distribution Width is a part of CBC (Complete Blood Count). If the number of large platelets is high in a patient with a low platelet count, it is an indicator that the bone marrow is now producing sufficient level of platelets. Smaller platelets have been around for several days. Ideally, younger platelets are large in size. It is significant in determining the functions of the bone marrow. It measures the platelet’s uniformity in size. PDW stands for Platelet Distribution Width. Please note : Immature platelet fraction normal range and its uses It will be extremely difficult for the body to clot the blood during bleeding because of inadequate amount of platelet. Patients suffering from thrombocytopenia are prone to bleeding. Over activity of the spleen – A hyperactive spleen can lead to a low mean platelet volume reading.Ī very low mean platelet volume is known as thrombocytopenia.Examples are haemolytic disorder, lupus, leukemia, aplastic anemia, and rheumatoid arthritis. Genetic disorder/autoimmune disorder – Patients suffering from genetic conditions have low mean platelet volume.Side effects of medications – Some drugs lowers MPV such as heparin.Viral Infection – A low platelet count indicates that you are suffering from viral infection such as Dengue fever and AIDS.Chances are, before the blood is tested it already undergone clotting. Error in collecting blood sample – One of the reasons for low MPV is mistakes in collecting blood samples.
Low MPV could indicate many diseases and disorders.Ī low MPV is an indicator that the platelet in the blood is lower than normal, which puts you at risk for severe blood loss if you get injured. If you sustain an injury, you will be prone to blood loss due to excessive bleeding because the blood does not have enough clotting factor. If your body does not have adequate level of platelet, it puts you at risk for bleeding. If the MPV is lower than the normal range, it means that your platelet count is low. ( 2, 3) What does low mean platelet volume mean? Health conditions like hypertension and hyperlipidemia should be managed too or else the patient will be at risk for cardiac complications.
To bring the level of MPV to normal range, a person should quit smoking. In the case of acute ischemic cardiovascular event, the level of platelet is also checked. If the level of platelet is high, it could indicate that you are suffering from acute myocardial infarction. Platelet plays a huge role in the blood coagulation process.